lookbook-
Top-Peponi's lda cat lady sweater(EB awarness event)
@peponi's
bottoms-{T.O.D}Worn blue jeans@The designer market exclusive
heels-THD work heels(nude)
@THD
ABOUT EB-
Epidermolysis Bullosa (EB) is a rare genetic connective tissue disorder, affecting 1 out of every 20,000 live births. There are many variations of EB, but all share the prominent symptom of extremely fragile skin that blisters and tears from minor friction or trauma. There is no cure.
Epidermolysis Bullosa (EB) — The Worst Disease You've Never Heard Of.
EB is caused by mutations in the DNA code that make up genes. Genes are responsible for making and expressing proteins. EB can result from one genetic mutation in any one of the 18 genes that have been found to cause the disorder. These mutations, or errors in the genetic code, may not allow the affected gene to produce a specific protein, or it may result in the incorrect formation of that protein. Either way, the mutation does not enable the affected protein to work correctly thus resulting in extremely fragile skin, and other manifestations of EB like: anemia, cardiomyopathy, syndactyly (fusion of the fingers and toes), renal insufficiency, dysphagia (difficulty swallowing), malnourishment, cancer, constipation, osteoporosis, muscular dystrophy and pyloric atresia.
There are four types of genetically inherited EB: Simplex, Dystrophic, Junctional and Kindler. These four major types of EB differ phenotypically (what physical manifestations look like) and genotypically (the genetic makeup) as well as by the area of the skin where there is blistering, otherwise known as “the site of ultra-structural disruption or cleavage”. There is also an autoimmune form of the disorder called, EB Acquisita .
Children with EB are known as Butterfly children because their skin is as fragile as the wings of a butterfly.
There are about 30,000 people with EB in the United States.
EB affects both genders and every racial and ethnic background.
- See more at: http://www.debra.org/whatiseb#sthash.a9LR0CbU.dpuf
